The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Oct. 08, 2012
Applicant:
Ptc Therapeutics, Inc., South Plainfield, NJ (US);
Inventors:
Sergey V. Paushkin, Belle Mead, NJ (US);
Anuradha Bhattacharyya, Edison, NJ (US);
Bansri S. Furia, Edison, NJ (US);
Meenal Patel, Fairless Hills, PA (US);
Love Volkova, Upland, CA (US);
Assignee:
PTC THERAPEUTICS, INC., South Plainfield, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 5/12 (2006.01); C12N 5/16 (2006.01); C12N 5/22 (2006.01); C12N 15/12 (2006.01); C12N 15/79 (2006.01); C07K 14/705 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 5/16 (2013.01); C12N 15/1138 (2013.01); C12N 15/79 (2013.01); C07K 14/4707 (2013.01); C07K 14/705 (2013.01); C12N 2830/50 (2013.01);
Abstract
The present invention provides compounds and assays for the identification and validation of compounds for use in the treatment of spinal muscular atrophy (SMA), in which said compounds up-regulate the post-transcriptional expression of SMN1 or SMN2.