The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Dec. 27, 2006
Cornelius Bessler, Düsseldorf, DE;
Jörg Feesche, Erkrath, DE;
Stefan Evers, Mettmann, DE;
Karl-heinz Maurer, Erkrath, DE;
Armin Ehrenreich, Göttingen, DE;
Birgit Veith, Göttingen, DE;
Heiko Liesegang, Höxter, DE;
Anke Henne, Solingen, DE;
Christina Herzberg, Bilshausen, DE;
Gerhard Gottschalk, Nörten-Hardenberg, DE;
Cornelius Bessler, Düsseldorf, DE;
Jörg Feesche, Erkrath, DE;
Stefan Evers, Mettmann, DE;
Karl-Heinz Maurer, Erkrath, DE;
Armin Ehrenreich, Göttingen, DE;
Birgit Veith, Göttingen, DE;
Heiko Liesegang, Höxter, DE;
Anke Henne, Solingen, DE;
Christina Herzberg, Bilshausen, DE;
Gerhard Gottschalk, Nörten-Hardenberg, DE;
BASF SE, Ludwigshafen, DE;
Abstract
The present invention relates to 25 hitherto undescribed genes ofand gene products derived therefrom and all sufficiently homologous nucleic acids and proteins thereof. They occur in five different metabolic pathways for the formation of odorous substances. The metabolic pathways in question are for the synthesis of: 1) isovalerian acid (as part of the catabolism of leucine), 2) 2-methylbutyric acid and/or isobutyric acid (as part of the catabolism of valine and/or isoleucine), 3) butanol and/or butyric acid (as part of the metabolism of butyric acid), 4) propyl acid (as part of the metabolism of propionate) and/or 5) cadaverine and/or putrescine (as parts of the catabolism of lysine and/or arginine). The identification of these genes allows biotechnological production methods to be developed that are improved to the extent that, to assist these nucleic acids, the formation of the odorous substances synthesized via these metabolic pathways can be reduced by deactivating the corresponding genes in the micro-organism used for the biotechnological production. In addition, these gene products are thus available for preparing reactions or for methods according to their respective biochemical properties.