The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Apr. 26, 2011
Applicants:
Jun Namiki, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Inventors:
Jun Namiki, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Assignee:
Keio University, Minato-ku, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0797 (2010.01); A61K 38/17 (2006.01); C12N 5/06 (2006.01); C12N 5/00 (2006.01); C12N 5/07 (2010.01); A61K 38/47 (2006.01); C12N 9/42 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0623 (2013.01); A61K 38/1709 (2013.01); A61K 38/1735 (2013.01); A61K 38/47 (2013.01); C12N 5/0018 (2013.01); C12N 5/06 (2013.01); C12N 9/2442 (2013.01); C12Y 302/01014 (2013.01); C12N 2501/73 (2013.01);
Abstract
An object of the present invention to provide an agent for promoting the self-renewal of the neural stem cells and a method of using the same. ECF-L contained in a culture supernatant of endothelial progenitor cells derived from bone marrow has an effect of promoting the self-renewal of neural stem cells. Accordingly, ECF-L can be used as an ingredient of an agent for promoting the self-renewal of the neural stem cells, a pharmaceutical composition for growing the neural stem cells, and a pharmaceutical composition for treating a disease associated with neural dysfunction.