The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2016

Filed:

Jun. 22, 2010
Applicants:

Ryosuke Takahashi, Kawagoe, JP;

Akiko Hisada, Kawagoe, JP;

Hiroshi Sonoda, Tsurugashima, JP;

Taku Saito, Tokyo, JP;

Inventors:

Ryosuke Takahashi, Kawagoe, JP;

Akiko Hisada, Kawagoe, JP;

Hiroshi Sonoda, Tsurugashima, JP;

Taku Saito, Tokyo, JP;

Assignee:

Hitachi, Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); C12N 5/00 (2006.01); C12M 1/32 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); C12M 21/08 (2013.01); C12M 23/12 (2013.01); C12M 25/06 (2013.01); C12N 2535/10 (2013.01);
Abstract

Disclosed is a culture sheet which enables technology in which three-dimensional tissues with uniform diameter are formed without applying chemicals to the surface of a culture substrate. A plurality of holes are formed on the culture sheet of the substrate, and nanopillars capable of controlling the adhesiveness or migration of a cell are formed on a culture surface that serves as the bottom surface of each of the holes. The culture surface of each of the holes having a structure in which a partition wall is provided, wherein, by forming the internal nanopillars in the vicinity of the center of each of the holes, the interaction of the disseminated cells can be limited to uniform the size of the three-dimensional structures of the cells to be formed.


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