The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2016

Filed:

Oct. 24, 2008
Applicants:

Kim D. Janda, San Diego, CA (US);

Gunnar F. Kaufmann, San Diego, CA (US);

Junguk Park, San Diego, CA (US);

Inventors:

Kim D. Janda, San Diego, CA (US);

Gunnar F. Kaufmann, San Diego, CA (US);

Junguk Park, San Diego, CA (US);

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 17/00 (2006.01); C07K 16/44 (2006.01); C07K 16/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); C07K 16/1271 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The invention provides an immunogenic molecular entity, a supramolecular assembly, and an antibody that can be used to inhibit Gram-positive bacterial quorum sensing, prevent infection or development of a disease condition associated with a Gram-positive bacterial infection. The invention also provides methods of inhibiting Gram-positive bacterial quorum sensing, and methods of preventing infection or development of a disease condition associated with a Gram-positive bacterial infection.


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