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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9394303 B1

PDFFull Text
Date of Patent:
Jul. 19, 2016

Filed:

Apr. 03, 2015

Small molecule inhibitors of mcl-1 and uses thereof

Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Zaneta Nikolovska-Coleska, Ann Arbor, MI (US);

Fardokht Abulwerdi, Frederick, MD (US);

Hollis Showalter, Ann Arbor, MI (US);

Lei Miao, Ann Arbor, MI (US);

Jeanne Stuckey, Fenton, MI (US);

Ahmed Mady, Ann Arbor, MI (US);

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);

Attorney:

Casimir Jones, SC

Primary Examiner:

Niloofar Rahmani

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); A61N 2005/1098 (2013.01);
Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having pyrazolopyridine structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases.

Find Patent Forward Citations

Nikolovska-Coleska, Zaneta. (2016). Small molecule inhibitors of mcl-1 and uses thereof (U.S. Patent No. 9394303). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9394303

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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