The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Mar. 24, 2015
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Paul S. Charifson, Framington, MA (US);
Michael P. Clark, Concord, MA (US);
Upul K. Bandarage, Lexington, MA (US);
Randy S. Bethiel, Lexington, MA (US);
Michael J. Boyd, Winchester, MA (US);
Ioana Davies, Arlington, MA (US);
Hongbo Deng, Southborough, MA (US);
John P. Duffy, Northborough, MA (US);
Luc J. Farmer, Montreal, CA;
Huai Gao, Arlington, MA (US);
Wenxin Gu, Concord, MA (US);
Joseph M. Kennedy, Charlestown, MA (US);
Brian Ledford, Norton, MA (US);
Mark W. Ledeboer, Acton, MA (US);
Francois Maltais, Tewksbury, MA (US);
Emanuele Perola, Brookline, MA (US);
Tiansheng Wang, Concord, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
This invention provides methods of preparing 3-(pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridines and 3-(pyrimidin-2-yl)-1H-pyrazolo[3,4-b]pyridines, or pharmaceutically acceptable salts thereof that are useful for inhibiting the replication of influenza viruses in a biological sample or patient, reducing the amount of influenza viruses in a biological sample or patient, and treating influenza in a patient.