The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 19, 2016

Filed:

Sep. 24, 2013
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Samit Kumar Bhattacharya, Waltham, MA (US);

Kimberly O'Keefe Cameron, Cambridge, MA (US);

Matthew Scott Dowling, Groton, CT (US);

David Christopher Ebner, Somerville, MA (US);

David James Edmonds, Arlington, MA (US);

Dilinie Prasadhini Fernando, Niantic, CT (US);

Kevin James Filipski, Reading, MA (US);

Daniel Wei-Shung Kung, Salem, CT (US);

Esther Cheng Yin Lee, Brookline, MA (US);

Aaron Christopher Smith, North Providence, RI (US);

Meihua Mike Tu, Acton, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 403/12 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); A61K 31/404 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61P 13/12 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/4439 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01);
Abstract

The present invention relates to indole and indazole compounds of Formula (I) that activate 5' adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.


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