The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Jun. 30, 2014
Applicant:
Tekmira Pharmaceuticals Corporation, Burnaby, CA;
Inventors:
Jianxin Chen, Cambridge, MA (US);
Steven Ansell, Cambridge, MA (US);
Akin Akinc, Cambridge, MA (US);
Joseph Robert Dorkin, Cambridge, MA (US);
Xiaojun Qin, Cambridge, MA (US);
William Cantley, Cambridge, MA (US);
Muthiah Manoharan, Cambridge, MA (US);
Kallanthottathil G. Rajeev, Cambridge, MA (US);
Jayaprakash K. Narayanannair, Cambridge, MA (US);
Muthusamy Jayaraman, Cambridge, MA (US);
Assignee:
Arbutus Biopharma Corporation, Burnaby, BC, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 227/00 (2006.01); C07B 43/00 (2006.01); C07C 227/18 (2006.01); A61K 9/127 (2006.01); A61K 31/22 (2006.01); A61K 31/7088 (2006.01); A61K 38/17 (2006.01); A61K 38/48 (2006.01); C07C 229/12 (2006.01); C07D 475/04 (2006.01); C12N 15/113 (2010.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61K 47/14 (2006.01); C07C 29/58 (2006.01); C07C 227/40 (2006.01);
U.S. Cl.
CPC ...
C07C 227/18 (2013.01); A61K 9/1272 (2013.01); A61K 9/1278 (2013.01); A61K 31/22 (2013.01); A61K 31/7088 (2013.01); A61K 38/1709 (2013.01); A61K 38/4846 (2013.01); A61K 47/14 (2013.01); A61K 47/48092 (2013.01); A61K 47/48107 (2013.01); A61K 47/48815 (2013.01); A61K 48/0033 (2013.01); C07C 29/58 (2013.01); C07C 227/40 (2013.01); C07C 229/12 (2013.01); C07D 475/04 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/341 (2013.01); C12N 2310/346 (2013.01); C12N 2310/351 (2013.01); C12N 2320/32 (2013.01);
Abstract
The invention features a cationic lipid of formula I, Also disclosed are targeting lipids, and specific lipid formulations comprising such targeting lipids.