The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Jan. 22, 2014
Applicant:
Waters Technologies Corporation, Milford, MA (US);
Inventors:
Geoff C. Gerhardt, Millbury, MA (US);
Joseph A. Luongo, Walpole, MA (US);
Assignee:
Waters Technologies Corporation, Milford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/16 (2006.01); B01L 3/00 (2006.01); F04B 13/02 (2006.01); F04B 23/04 (2006.01); G01N 30/32 (2006.01);
U.S. Cl.
CPC ...
B01D 15/163 (2013.01); B01L 3/50273 (2013.01); F04B 13/02 (2013.01); F04B 23/04 (2013.01); G01N 30/32 (2013.01); B01L 2200/143 (2013.01); B01L 2400/086 (2013.01); F04B 2205/09 (2013.01); G01N 2030/324 (2013.01);
Abstract
A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<1 μL/min) HPLC flow rates.