The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Aug. 02, 2014
Christopher Patrick Marshall, New York, NY (US);
Peter Joseph Alff, New York, NY (US);
Claudio Bertuccioli, New York, NY (US);
Mark Andrew Yondola, Medford, NY (US);
Christopher Patrick Marshall, New York, NY (US);
Peter Joseph Alff, New York, NY (US);
Claudio Bertuccioli, New York, NY (US);
Mark Andrew Yondola, Medford, NY (US);
AVATAR MEDICAL, LLC, New York, NY (US);
Abstract
In some embodiments the present invention provides influenza hemagglutinin ('HA') polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.