The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Oct. 18, 2012
Applicant:
Csl Behring Gmbh, Marburg, DE;
Inventors:
Hubert Metzner, Marburg, DE;
Sabine Zollner, Muri, CH;
Assignee:
CSL Behring GmbH, Marburg, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 16/00 (2006.01); A61K 38/37 (2006.01); A61K 47/36 (2006.01); A61K 9/00 (2006.01); A61K 47/42 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01); A61K 9/0019 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01);
Abstract
The present invention relates to pharmaceutical preparations comprising one or more Factor VIII and a sulfated glycosaminoglycan for increasing the bioavailability of Factor VIII upon non-intravenous administration. The invention further relates to the combined use of Factor VIII and a sulfated glycosaminoglycan for the treatment and prevention of bleeding disorders, whereby the bioavailability of Factor VIII is increased, and to a method for increasing the bioavailability after non-intravenous administration of Factor VIII by coadminstration of a sulfated glycosaminoglycan.