The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 2016
Filed:
Jan. 14, 2013
Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Praha, CZ;
Vyzkumny Ustav Veterinarniho Lekarstvi, V.v.i., Brno, CZ;
Lukas Drasar, Praha, CZ;
Miroslav Ledvina, Praha, CZ;
Zina Korvasova, Brno, CZ;
Jaroslav Turanek, Brno, CZ;
USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., Praha, CZ;
Abstract
The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C—N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy-alkylcarboxamide linker or ω-hydroxyalkylcarboxamidopolyethyleneglycol-carboxamide linker, and wherein a hydrophobic domain Y is an acyl symmetrically branched in the position C(2) or cholesteryl. The invention further provides a method of preparation of said lipopolyamines and their use for construction of polycationic liposomal drug carriers.