The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Mar. 26, 2012
Joost Schymkowitz, Meensel-Kiezegem, BE;
Frederic Rousseau, Groot-Bijgaarden, BE;
Jie Xu, Shanghai, CN;
Frederik DE Smet, Winksele, BE;
Joost Schymkowitz, Meensel-Kiezegem, BE;
Frederic Rousseau, Groot-Bijgaarden, BE;
Jie Xu, Shanghai, CN;
Frederik De Smet, Winksele, BE;
Vrije Universiteit Brussel, Brussel, BE;
Katholieke Universiteit Leuven, K.U. Leuven R&D, Leuven, BE;
Abstract
The disclosure relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt co-aggregation of one or more member proteins of a disease-related protein aggregome, in particular, a tumor-associated protein aggregome. Further, disclosed are agents and compounds identified by the screening method that can be applied to prevent or to treat protein aggregation diseases, such as cancer.