The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Mar. 24, 2014
Applicant:
The Trustees of Princeton University, Princeton, NJ (US);
Inventors:
Robert H. Austin, Princeton, NJ (US);
Zhaoning Yu, Princeton, NJ (US);
Jonas O. Tegenfeldt, Lund, SE;
Stephen Y. Chou, Princeton, NJ (US);
Han Cao, San Diego, CA (US);
Assignee:
The Trustees of Princeton University, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12M 1/34 (2006.01); G01N 15/06 (2006.01); G01N 21/00 (2006.01); C07H 21/02 (2006.01); B01D 61/42 (2006.01); C40B 10/00 (2006.01); C40B 40/06 (2006.01); G01N 33/487 (2006.01); B01L 3/00 (2006.01); B81B 1/00 (2006.01); B81C 1/00 (2006.01); B82Y 30/00 (2011.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); B01L 3/502707 (2013.01); B81B 1/002 (2013.01); B81C 1/00071 (2013.01); B82Y 30/00 (2013.01); G01N 21/648 (2013.01); G01N 21/6428 (2013.01); B01J 2219/00274 (2013.01); B01L 2200/0663 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0896 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/086 (2013.01); B81B 2201/058 (2013.01); C12Q 1/6837 (2013.01); Y10S 977/704 (2013.01); Y10S 977/88 (2013.01); Y10S 977/883 (2013.01);
Abstract
Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods.