The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Aug. 03, 2007
Applicants:

Svein Valla, Trondheim, NO;

Rahmi Lale, Trondheim, NO;

Laila Berg, Trondheim, NO;

Ingrid Bakke, Ranheim, NO;

Inventors:

Svein Valla, Trondheim, NO;

Rahmi Lale, Trondheim, NO;

Laila Berg, Trondheim, NO;

Ingrid Bakke, Ranheim, NO;

Assignee:

VECTRON BIOSOLUTIONS AS, Trondheim, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01);
Abstract

The present invention concerns a method of producing a desired heterologous gene product wherein said heterologous gene product is expressed from a strong promoter, said method comprising expressing said gene using a mutant mRNA leader which comprises one or more mutations which enhance transcription of the gene. The invention also provides a mutant Pm mRNA leader sequence, and a vector and a library comprising the leader sequence. Methods of obtaining an mRNA mutant leader and identifying an mRNA mutant leader are encompassed, along with a vector for selection or identification of an mRNA leader mutant and a use thereof for screening.


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