The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Sep. 06, 2012
Thomas Thum, Hannover, DE;
Kamal Chowdhury, Goettingen, DE;
Ahmet Ucar, Heidelberg, DE;
Shashi Kumar Gupta, Hannover, DE;
Thomas Thum, Hannover, DE;
Kamal Chowdhury, Goettingen, DE;
Ahmet Ucar, Heidelberg, DE;
Shashi Kumar Gupta, Hannover, DE;
Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V., Munich, DE;
Medizinische Hochschule Hannover, Hannover, DE;
Abstract
The present invention refers to inhibitors of microRNAs, particularly of microRNAs miR-212 and/or miR-132 for use in medicine, particularly in the diagnosis, treatment or prevention of cardiac disorders, e.g. cardiac hypertrophy-associated or autophagic disorders, and further refers to isolated nucleic acid molecules, particularly microRNAs miR-212 and/or miR-132 and related sequences, for use in medicine, particularly human medicine, more particularly in the diagnosis, treatment or prevention of disorders involving cardiac atrophy and/or dysfunctional autophagy, e.g. cardiac cachexia.