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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9388381 B1

PDFFull Text
Date of Patent:
Jul. 12, 2016

Filed:

Jul. 09, 2010

Methods and compositions for increased safety of stem cell-derived populations

Applicants:

Clark K. Colton, Newton, MA (US);

Jeffrey R. Millman, St. Louis, MO (US);

Inventors:

Clark K. Colton, Newton, MA (US);

Jeffrey R. Millman, St. Louis, MO (US);

Assignee:

Massachusetts Institute of Technology, Cambridge, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Renee Claytor

Assistant Examiner:

David Berke-Schlessel

Int. Cl.
CPC ...
A61K 35/12 (2015.01); C12N 5/077 (2010.01); C12Q 1/02 (2006.01); C12N 5/071 (2010.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); C12N 5/0696 (2013.01); C12N 2500/02 (2013.01);
Abstract

The invention provides methods and compositions relating to differentiated cell populations that derive from pluripotent stem cells. The methods relate to reducing the number of residual stem cells present in such populations. The compositions include differentiated cell populations that contain reduced number of stem cells or that contain no stem cells. Pluripotent stem cells may be reduced in number and/or function through exposure to low oxygen levels.

Find Patent Forward Citations

Colton, Clark. (2016). Methods and compositions for increased safety of stem cell-derived populations (U.S. Patent No. 9388381). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9388381

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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