The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

May. 05, 2011
Applicants:

Laurent Gauthier, Marseilles, FR;

Catherine Massacrier, Tassin la demi lune, FR;

Yannis Morel, Marseilles, FR;

Carine Paturel, Marcy l'E-toile, FR;

Inventors:

Laurent Gauthier, Marseilles, FR;

Catherine Massacrier, Tassin la demi lune, FR;

Yannis Morel, Marseilles, FR;

Carine Paturel, Marcy l'E-toile, FR;

Assignee:

INNATE PHARMA, Marseilles, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C12N 5/16 (2006.01); C12N 5/10 (2006.01); A61P 31/00 (2006.01); A61P 37/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); C07K 2317/34 (2013.01); C07K 2317/54 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to antibodies (e.g. monoclonal antibodies), antibody fragments, and derivatives thereof that specifically bind TLR3, and that optionally further modulate, e.g. inhibit, signaling. The invention also relates to cells producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; pharmaceutical compositions comprising the same; methods of using the antibodies to diagnose, treat or prevent diseases, e.g. autoimmune diseases, inflammatory diseases and the like.


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