The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
May. 29, 2014
Samsung Electronics Co., Ltd., Suwon-si, Gyeonggi-do, KR;
Kwang Ho Cheong, Seoul, KR;
Seung Hyun Lee, Suwon-si, KR;
Mi Young Cho, Seoul, KR;
Young Jun Koh, Yongin-si, KR;
Lin Powei, Hwaseong-si, KR;
Christina Yi, Seongnam-si, KR;
Jae Woong Hwang, Seoul, KR;
SAMSUNG ELECTRONICS CO., LTD., Suwon-Si, KR;
Abstract
A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.