The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Dec. 15, 2014
Applicant:
Imaxio, Paris, FR;
Inventors:
Assignee:
Imaxio, , FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/47 (2006.01); A61K 39/002 (2006.01); A61K 39/04 (2006.01); A61K 39/085 (2006.01); A61K 39/12 (2006.01); A61K 39/385 (2006.01); C07K 7/06 (2006.01); C07K 14/005 (2006.01); C07K 14/31 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 39/002 (2013.01); A61K 39/0005 (2013.01); A61K 39/0006 (2013.01); A61K 39/04 (2013.01); A61K 39/085 (2013.01); A61K 39/12 (2013.01); A61K 39/385 (2013.01); C07K 7/06 (2013.01); C07K 14/005 (2013.01); C07K 14/31 (2013.01); C12N 7/00 (2013.01); A61K 39/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/627 (2013.01); A61K 2039/64 (2013.01); C07K 2319/00 (2013.01); C07K 2319/40 (2013.01); C07K 2319/73 (2013.01); C12N 2760/16034 (2013.01); C12N 2760/16134 (2013.01);
Abstract
The present application is related to a modified protein comprising a protein having a coiled coil domain and a peptide having the sequence such as shown in SEQ ID NO 1: ZXBBBBZ that is linked to the coiled coil domain wherein: Said modified protein is in particular an antigen or a carrier protein, associated to an antigen. This modified protein has an increased affinity for negatively charged polymers such as nucleic acids or heparin, and shows an increased immunogenicity.