The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Feb. 24, 2012
Applicants:

Douglas Covey, St. Louis, MO (US);

Eva Kudova, Prague, CZ;

Inventors:

Douglas Covey, St. Louis, MO (US);

Eva Kudova, Prague, CZ;

Assignee:

WASHINGTON UNIVERSITY, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 41/00 (2006.01); C07J 1/00 (2006.01); C07J 13/00 (2006.01); C07J 3/00 (2006.01); C07J 7/00 (2006.01); C07J 21/00 (2006.01);
U.S. Cl.
CPC ...
C07J 41/0094 (2013.01); C07J 1/0011 (2013.01); C07J 3/00 (2013.01); C07J 7/002 (2013.01); C07J 13/005 (2013.01); C07J 21/008 (2013.01);
Abstract

The present disclosure is generally directed to neuroactive 17(20)-Z-vinylcyano-substituted compound of Formula (I) and (II), as referenced herein, and pharmaceutically acceptable salts thereof, for use as, for example, an anesthetic, and/or in the treatment of disorders relating to GABA function and activity. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.


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