The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Feb. 22, 2013
Applicant:

Lupin Limited, Mumbai, Maharashtra, IN;

Assignee:

Lupin Limited, Mumbai, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/5386 (2006.01); A61K 31/454 (2006.01); A61K 31/439 (2006.01); A61K 31/427 (2006.01); C07D 417/14 (2006.01); C07D 417/06 (2006.01); C07D 417/04 (2006.01); C07D 498/08 (2006.01); C07D 277/56 (2006.01); C07D 221/22 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); A61K 31/427 (2013.01); A61K 31/439 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 45/06 (2013.01); C07D 221/22 (2013.01); C07D 277/56 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01);
Abstract

Disclosed is a compound of formula (I) wherein Y, Ring D, m and R-Rare as described herein, as a modulator of nicotinic acetylcholine receptors particularly the α7 subtype, in a subject in need thereof, as well as pharmaceutically acceptable salts, polymorphs, solvates, and isomers thereofs, for use either alone or in combinations with suitable other medicaments, and pharmaceutical compositions containing such compounds. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and therapy of disorders such as Alzheimer's disease, mild cognitive impairment, senile dementia, and the like.


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