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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9388179 B1

PDFFull Text
Date of Patent:
Jul. 12, 2016

Filed:

Oct. 23, 2013

N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Joseph E. Pero, Harleysville, PA (US);

Hannah D. G. F. Lehman, Boyertown, PA (US);

Mark E. Layton, Harleysville, PA (US);

Michael A. Rossi, Middletown, DE (US);

Michael J. Kelly, III, Paoli, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

John C. Todaro

H. Eric Fischer

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 417/12 (2006.01); A61K 31/416 (2006.01); C07D 471/08 (2006.01); C07D 401/14 (2006.01); C07D 231/56 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01); C07D 231/56 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

Disclosed are compounds of Formula Aand Formula A: wherein 'Heteroaryl-1', R, R, R, and Rare defined herein, which novel compounds have properties for blocking Na1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formulae Aand Aor their salts, and methods of treating neuropathic pain disorders using the same.

Find Patent Forward Citations

Pero, Joseph. (2016). N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels (U.S. Patent No. 9388179). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9388179

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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