The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Aug. 27, 2013
Applicants:
Array Biopharma Inc., Boulder, CO (US);
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Jim Blake, Boulder, CO (US);
Huifen Chen, South San Francisco, CA (US);
Mark Chicarelli, Boulder, CO (US);
John Gaudino, Boulder, CO (US);
Lewis Gazzard, South San Francisco, CA (US);
Sam Kintz, South San Francisco, CA (US);
Pete Mohr, Boulder, CO (US);
Kirk Robarge, South San Francisco, CA (US);
Jacob Schwarz, South San Francisco, CA (US);
Aihe Zhou, South San Francisco, CA (US);
Assignees:
GENETECH, INC., South San Francisco, CA (US);
ARRAY BIOPHARMA INC., Boulder, CO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 217/22 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); A61K 31/4725 (2006.01); A61K 31/4375 (2006.01); A61K 31/472 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); C07D 217/22 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01);
Abstract
Compounds having the formula I wherein R, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.