The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Oct. 23, 2013
Applicant:

Pharmaleads, Paris, FR;

Inventors:
Assignee:

PHARMALEADS, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/00 (2006.01); C07C 321/14 (2006.01); C07C 323/56 (2006.01); C07C 323/61 (2006.01); A61K 31/216 (2006.01); A61K 31/221 (2006.01); A61K 31/27 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 321/14 (2013.01); A61K 31/216 (2013.01); A61K 31/221 (2013.01); A61K 31/27 (2013.01); A61K 45/06 (2013.01); C07C 323/56 (2013.01); C07C 323/61 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2101/16 (2013.01); C07C 2102/08 (2013.01);
Abstract

Mixed inhibitors of aminopeptidase N and neprilysin are disclosed. Pharmaceutical compositions containing at least one of these compounds, used alone or in combination with morphine and derivatives thereof, endocannabinoids and inhibitors of endocannabinoid metabolism, GABA derivatives such as gabapentin or pregabalin, duloxetine or methadone, can be used as an analgesic, anxiolytic, antidepressant or anti-inflammatory.


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