The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Jan. 06, 2011
Applicants:

Marianne D. Sadar, West Vancouver, CA;

Nasrin R. Mawji, Burnaby, CA;

Carmen Adriana Banuelos, Vancouver, CA;

Raymond J. Andersen, Vancouver, CA;

Javier Garcia Fernandez, Gijon, ES;

Inventors:

Marianne D. Sadar, West Vancouver, CA;

Nasrin R. Mawji, Burnaby, CA;

Carmen Adriana Banuelos, Vancouver, CA;

Raymond J. Andersen, Vancouver, CA;

Javier Garcia Fernandez, Gijon, ES;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 43/23 (2006.01); C07D 401/06 (2006.01); C07C 15/16 (2006.01); C07C 57/38 (2006.01); A61K 31/09 (2006.01); A61K 31/22 (2006.01); C07C 69/63 (2006.01); C07C 43/225 (2006.01);
U.S. Cl.
CPC ...
C07C 57/38 (2013.01); A61K 31/09 (2013.01); A61K 31/22 (2013.01); C07C 15/16 (2013.01); C07C 43/225 (2013.01); C07C 43/23 (2013.01); C07C 69/63 (2013.01); C07D 401/06 (2013.01);
Abstract

This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.


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