The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Mar. 31, 2014
Applicant:

The Governing Council of the Univeristy of Toronto, Toronto, CA;

Inventors:

Xiao Yu Wu, Toronto, CA;

Kai Zhang, Brampton, CA;

Huiyu Huang, Toronto, CA;

Claudia Gordijo, Toronto, CA;

Jason Siu-Wei Li, Toronto, CA;

Michael K.L. Chu, Toronto, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61M 31/00 (2006.01); A61L 31/04 (2006.01); A61M 5/142 (2006.01);
U.S. Cl.
CPC ...
A61L 31/041 (2013.01); A61M 5/14276 (2013.01); A61M 2205/0227 (2013.01); A61M 2230/201 (2013.01);
Abstract

A biocompatible insulin delivery device is provided comprising an insulin reservoir sealed with a glucose-responsive plug or membrane. The plug functions to release insulin from the reservoir in response to a hyperglycemic glucose concentration and to prevent insulin release from the reservoir in response to hypoglycemic glucose concentration. In one embodiment, the plug is made of a biocompatible polymeric matrix comprising an inorganic component, a stimulus-responsive component and a catalytic component.


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