The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Nov. 21, 2012
Applicants:

Daya Verma, Edison, NJ (US);

Yogita Krishnamachan, Springfield, NJ (US);

Xiaohong Shen, Livingston, NJ (US);

Hanchen Lee, Teaneck, NJ (US);

Ping LI, Basking Ridge, NJ (US);

Rajinder Singh, Sewaren, NJ (US);

Laychoo Tan, Bridgewater, NJ (US);

Inventors:

Daya Verma, Edison, NJ (US);

Yogita Krishnamachan, Springfield, NJ (US);

Xiaohong Shen, Livingston, NJ (US);

Hanchen Lee, Teaneck, NJ (US);

Ping Li, Basking Ridge, NJ (US);

Rajinder Singh, Sewaren, NJ (US);

LayChoo Tan, Bridgewater, NJ (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01); A61K 9/2031 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01);
Abstract

This invention relates to solid oral pharmaceutical formulations of (S)-methyl (1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate (COMPOUND A) and the use of the formulations for treating proliferative diseases, such as solid tumor diseases.


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