The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
Aug. 03, 2012
Keietsu Abe, Sendai, JP;
Kazuyoshi Kawakami, Sendai, JP;
Tadafumi Ajiri, Sendai, JP;
Manabu Fukumoto, Sendai, JP;
Seiichi Takami, Sendai, JP;
Takanari Togashi, Sendai, JP;
Kimihide Muragaki, Sendai, JP;
Toru Takahashi, Sendai, JP;
Keietsu Abe, Sendai, JP;
Kazuyoshi Kawakami, Sendai, JP;
Tadafumi Ajiri, Sendai, JP;
Manabu Fukumoto, Sendai, JP;
Seiichi Takami, Sendai, JP;
Takanari Togashi, Sendai, JP;
Kimihide Muragaki, Sendai, JP;
Toru Takahashi, Sendai, JP;
TOHOKU UNIVERSITY, Miyagi, JP;
Abstract
It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.