The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2016

Filed:

Feb. 24, 2014
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

The United States of America As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

David Myung, Santa Clara, CA (US);

Lampros Kourtis, San Francisco, CA (US);

Laura Hartmann, Berlin, DE;

Curtis W. Frank, Cupertino, CA (US);

Stuart B. Goodman, Los Altos, CA (US);

Dennis R. Carter, Stanford, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/30 (2006.01); A61F 2/38 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61F 2/34 (2006.01); A61F 2/36 (2006.01); A61F 2/42 (2006.01); A61F 2/44 (2006.01);
U.S. Cl.
CPC ...
A61F 2/30756 (2013.01); A61F 2/3872 (2013.01); A61L 27/3843 (2013.01); A61L 27/52 (2013.01); A61F 2/34 (2013.01); A61F 2/3603 (2013.01); A61F 2/4202 (2013.01); A61F 2/4225 (2013.01); A61F 2/4241 (2013.01); A61F 2/4405 (2013.01); A61F 2002/30075 (2013.01); A61F 2002/30448 (2013.01); A61F 2002/30754 (2013.01); A61F 2002/3619 (2013.01); A61F 2210/0061 (2013.01); A61F 2220/005 (2013.01); A61F 2310/00293 (2013.01); A61L 2430/24 (2013.01);
Abstract

An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.


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