The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Feb. 11, 2014
Applicant:
National Jewish Health, Denver, CO (US);
Inventors:
Nathan Rabinovitch, Denver, CO (US);
Erwin Gelfand, Englewood, CO (US);
Assignee:
National Jewish Health, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); G01N 33/50 (2006.01); G01N 33/88 (2006.01); G01N 33/497 (2006.01);
U.S. Cl.
CPC ...
G01N 33/88 (2013.01); A61K 31/47 (2013.01); G01N 33/497 (2013.01); G01N 2033/4975 (2013.01); G01N 2800/24 (2013.01); G01N 2800/52 (2013.01); Y10T 436/177692 (2015.01);
Abstract
The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and the subject's level of eosinophilic airway inflammation and identifying a subject with a high ratio of CysLT levels to eosinophilic airway inflammation as susceptible to treatment with the leukotriene modifier. Also discussed is a method of treatment of subjects who are susceptible to treatment that includes administering a leukotriene modifier to such a subject.