The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Nov. 27, 2013
Applicant:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Inventors:
Stefanie Froehner, Penzberg, DE;
Dieter Heindl, Paehl, DE;
Dirk Kessler, Peiting, DE;
Nancy Schoenbrunner, Moraga, CA (US);
Alison Tsan, Danville, CA (US);
Assignee:
ROCHE MOLECULAR SYSTEMS, INC., Pleasanton, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6853 (2013.01); C12Q 1/6858 (2013.01);
Abstract
The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having at least one selective nucleotide complementary to only one variant of the target sequence and incorporating both a nucleotide with a base covalently modified at the exocyclic amino group and a modified phosphate.