The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Feb. 26, 2014
Applicants:
Stanley Goldman, Walnut Creek, CA (US);
Mark Albrecht, Washington, DC (US);
Inventors:
Stanley Goldman, Walnut Creek, CA (US);
Mark Albrecht, Washington, DC (US);
Assignee:
The United States of America as represented by the Secretary of the Navy, Washington, DC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/64 (2006.01); A61K 39/07 (2006.01); C07K 14/32 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/64 (2013.01); A61K 39/07 (2013.01); C07K 14/32 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55511 (2013.01);
Abstract
The invention relates to a humanized nucleic acid construct fromprotective antigen (PA) gene and method of modifying the gene. The humanized gene, and method of producing it, improves the structural fidelity of expressed protein product, when produced in mammalian host cells, to native, bacterially produced protein. The construct is useful in nucleic acid based vaccine formulations against