The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Mar. 14, 2014
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Maria Jure-Kunkel, Plainsboro, NJ (US);
Laura J. Hefta, Pennington, NJ (US);
Marc Santoro, Yardley, PA (US);
Subinay Ganguly, Newtown, PA (US);
Edward L. Halk, Sunnyvale, CA (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/39 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01); C07K 2317/75 (2013.01); C12N 2740/15034 (2013.01);
Abstract
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.