The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Dec. 30, 2014
Kyoto University, Kyoto-shi, Kyoto, JP;
National Institute of Radiological Sciences, Chiba-shi, Chiba, JP;
Haruhisa Inoue, Kyoto, JP;
Hiroki Takeuchi, Kyoto, JP;
Ryosuke Takahashi, Kyoto, JP;
Makoto Higuchi, Chiba, JP;
Bin Ji, Chiba, JP;
Tetsuya Suhara, Chiba, JP;
KYOTO UNIVERSITY, Kyoto-Shi, JP;
NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES, Chiba-Shi, JP;
Abstract
This invention relates to a vaccine for preventing or treating tautopathy, comprising a vector, as an active ingredient, comprising a nucleic acid encoding a mutant tau protein linked to a secretion signal sequence, wherein the vaccine is capable of inducing an antibody against an (optionally phospholylated) tau protein in a subject in a more sustained manner compared with a case where the mutant tau protein is administered directly.