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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9382246 B1

PDFFull Text
Date of Patent:
Jul. 05, 2016

Filed:

Dec. 03, 2014

Inhibitors of bruton's tyrosine kinase

Applicant:

Pharmacyclics Llc, Sunnyvale, CA (US);

Inventors:

Zhaozhong J. Jia, San Mateo, CA (US);

Wei Chen, Fremont, CA (US);

William D. Thomas, San Jose, CA (US);

Assignee:

Pharmacyclics LLC, Sunnyvale, CA (US);

Attorney:

Foley Hoag LLP

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); A61K 31/4025 (2006.01); A61K 31/445 (2006.01); A61K 31/397 (2006.01); A61K 31/497 (2006.01); C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/397 (2013.01); A61K 31/4025 (2013.01); A61K 31/445 (2013.01); A61K 31/497 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

Find Patent Forward Citations

Jia, Zhaozhong. (2016). Inhibitors of bruton's tyrosine kinase (U.S. Patent No. 9382246). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9382246

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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