logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9382232 B1

PDFFull Text
Expired
Date of Patent:
Jul. 05, 2016

Filed:

Dec. 07, 2012

Quinoline and cinnoline derivatives and their applications

Applicants:

Shenyang Pharmaceutical University, Shenyang, CN;

Shenyang Pharmaceutical University (Benxi) Pharmaceutical Science and Technology Co., Ltd., Benxi, CN;

Inventors:

Ping Gong, Shenyang, CN;

Yanfang Zhao, Shenyang, CN;

Yajing Liu, Shenyang, CN;

Xin Zhai, Shenyang, CN;

Sai Li, Shenyang, CN;

Wufu Zhu, Shenyang, CN;

Mingze Qin, Shenyang, CN;

Assignees:

Shenyang Pharmaceutical University, Shenyang, CN;

Shenyang Pharmaceutical University (Benxi) Pharmaceutical Science and Technology Co., Ltd., Benxi, CN;

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Nyeemah A Grazier

Assistant Examiner:

Amanda L Aguirre

Int. Cl.
CPC ...
C07D 403/14 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); A61P 35/00 (2006.01); A61K 31/496 (2006.01); A61K 31/502 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 31/496 (2013.01); A61K 31/502 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01);
Abstract

The present invention relates to a series of quinoline and cinnoline derivatives of general formula I, pharmaceutically acceptable salts, hydrates, solvates or prodrugs thereof. And the compounds of general formula I show potent inhibitory activity gainst c-Met kinase. The present invention further relates to the uses of the compounds, pharmaceutically acceptable salts and hydrates for the preparation of medicaments for the treatment and/or prevention of diseases caused by abnormal expression of c-Met kinase, especially for treatment and/or prevention of cancer.

Find Patent Forward Citations

Quick Actions:

Gong, Ping. (2016). Quinoline and cinnoline derivatives and their applications (U.S. Patent No. 9382232). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9382232

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…