The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2016

Filed:

May. 09, 2013
Applicant:

Wista Laboratories Ltd., Singapore, SG;

Inventors:

Claude Michel Wischik, Aberdeen, GB;

John Mervyn David Storey, Old Aberdeen, GB;

Colin Marshall, Old Aberdeen, GB;

James Peter Sinclair, Old Aberdeen, GB;

Thomas Craven Baddeley, Old Aberdeen, GB;

Assignee:

WisTa Laboratories Ltd., Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 279/18 (2006.01); C07D 279/20 (2006.01);
U.S. Cl.
CPC ...
C07D 279/20 (2013.01); C07D 279/18 (2013.01);
Abstract

Described are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (referred to herein as 'diaminophenothiazinium compounds') including Methylthioninium Chloride (MTC) (also known as Methylene Blue), the resulting (high purity) compounds, compositions comprising such compounds (e.g., tablets, capsules), and the use of such high purity compounds. The compounds are useful in inactivating pathogens, and methods of medical treatment, prophylaxis, and diagnosis of diseases including a tauopathy, related neurological and infectious diseases.


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