The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Dec. 29, 2014
Applicant:
Emory University, Atlanta, GA (US);
Inventors:
Lanny S. Liebeskind, Atlanta, GA (US);
Wenting Wu, Decatur, GA (US);
Zhihui Zhang, New Berlin, WI (US);
Hao Li, Decatur, GA (US);
Angus A. Lamar, Atlanta, GA (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/08 (2006.01); C07C 231/02 (2006.01); C07C 233/65 (2006.01); C07C 233/69 (2006.01); C07C 233/07 (2006.01); C07D 213/82 (2006.01); C07D 233/90 (2006.01); C07D 295/192 (2006.01); C07D 307/52 (2006.01); C07F 7/18 (2006.01); C07H 1/00 (2006.01); C07H 21/02 (2006.01); C07K 1/00 (2006.01); C07K 1/02 (2006.01); C07K 5/062 (2006.01); C07K 5/065 (2006.01); C07K 5/068 (2006.01); C07K 5/072 (2006.01); C07K 5/087 (2006.01);
U.S. Cl.
CPC ...
C07C 231/02 (2013.01); C07C 233/07 (2013.01); C07C 233/65 (2013.01); C07C 233/69 (2013.01); C07D 213/82 (2013.01); C07D 233/90 (2013.01); C07D 295/192 (2013.01); C07D 307/52 (2013.01); C07F 7/1852 (2013.01); C07F 7/1856 (2013.01); C07H 1/00 (2013.01); C07H 21/02 (2013.01); C07K 1/003 (2013.01); C07K 1/02 (2013.01); C07K 5/0606 (2013.01); C07K 5/06026 (2013.01); C07K 5/06034 (2013.01); C07K 5/06078 (2013.01); C07K 5/06086 (2013.01); C07K 5/06104 (2013.01); C07K 5/0812 (2013.01);
Abstract
The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.