IDiyas

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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9381261 B1

PDFFull Text
Date of Patent:
Jul. 05, 2016

Filed:

Jun. 05, 2012

Shk-based pharmaceutical compositions and methods of manufacturing and using the same

Applicants:

Shawn P Iadonato, Seattle, WA (US);

Eric J Tarcha, Seattle, WA (US);

Inventors:

Shawn P Iadonato, Seattle, WA (US);

Eric J Tarcha, Seattle, WA (US);

Assignee:

Kineta One, LLC, Seattle, WA (US);

Attorney:
Primary Examiner:

James H Alstrum Acevedo

Assistant Examiner:

Thea D'Ambrosio

Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 1/00 (2006.01); B01L 3/00 (2006.01); G01N 31/22 (2006.01); G01N 33/52 (2006.01); A61K 51/08 (2006.01); C07K 14/00 (2006.01); A61K 38/17 (2006.01); C07K 14/435 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); B01L 3/12 (2006.01); B01L 9/00 (2006.01); B01L 99/00 (2010.01);
U.S. Cl.
CPC ...
A61K 51/088 (2013.01); A61K 38/16 (2013.01); A61K 38/1767 (2013.01); A61K 47/4803 (2013.01); A61K 49/0002 (2013.01); C07K 14/00 (2013.01); C07K 14/43504 (2013.01); B01L 3/12 (2013.01); B01L 9/00 (2013.01); B01L 99/00 (2013.01);
Abstract

Disclosed herein are pharmaceutical compositions having the sequence Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Xaa-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (SEQ ID NO: 1). The disclosed compositions can include an acid or amide at the C-terminus of SEQ ID NO: 1 and the polypeptide can be attached to an organic or inorganic chemical entity that has an anionic charge. The polypeptide can be detectably labeled for diagnostic purposes. Methods of manufacturing and using the pharmaceutical compounds are also disclosed.

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