The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 05, 2016

Filed:

Apr. 07, 2014
Applicant:

Nihon Medi-physics Co., Ltd., Tokyo, JP;

Inventors:

Osamu Ito, Chiba, JP;

Akio Hayashi, Chiba, JP;

Fumie Kurosaki, Chiba, JP;

Masahito Toyama, Chiba, JP;

Toshiyuki Shinmura, Chiba, JP;

Arinori Harano, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01); C07C 309/65 (2006.01); C07C 67/307 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0402 (2013.01); A61K 51/0406 (2013.01); C07B 59/00 (2013.01); C07C 67/307 (2013.01); C07C 309/65 (2013.01); C07B 2200/05 (2013.01); C07C 2101/04 (2013.01); Y02P 20/55 (2015.11);
Abstract

It is intended to provide a novel amino acid organic compound which can be used as a labeling precursor compound for radioactive halogen-labeled amino acid compounds including [F]FACBC, and which prevents methanol from remaining in the radioactive halogen-labeled amino acid compounds produced therefrom. The novel amino acid organic compound is a compound represented by the following formula: wherein n is an integer of 0 or of 1 to 4; Ris an ethyl, 1-propyl or isopropyl substituent; X is a halogen substituent or a group represented by —OR; Ris a straight-chain or branched-chain haloalkylsulfonic acid substituent with one to 10 carbon atoms, trialkylstannyl substituent with 3 to 12 carbon atoms, fluorosulfonic acid substituent or aromatic sulfonic acid substituent; and Ris a protective group.


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