The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Apr. 09, 2014
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Jeremiah A. Johnson, Boston, MA (US);
Longyan Liao, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 31/4745 (2006.01); A61K 31/704 (2006.01); C07F 15/00 (2006.01); A61K 31/555 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48176 (2013.01); A61K 31/4745 (2013.01); A61K 31/555 (2013.01); A61K 31/704 (2013.01); A61K 47/48215 (2013.01); C07F 15/0093 (2013.01);
Abstract
Described herein are platinum-based brush-arm star polymers (Pt-BASPs), or a pharmaceutical composition thereof, for delivery of platinum-based agents, such as cisplatin. Also provided are methods and kits involving the Pt-BASPs, or a pharmaceutical composition thereof, for treating proliferative diseases such as cancers (e.g., lung cancer, head-and-neck cancer, esophagus cancer, stomach cancer, breast cancer, pancreas cancer, liver cancer, kidney cancer, or prostate cancer) in a subject.