The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Feb. 20, 2014
Applicants:
President and Fellows of Harvard College, Cambridge, MA (US);
Forsyth Dental Infirmary for Children, Cambridge, MA (US);
Inventors:
Roger Warren Sands, Chicago, IL (US);
Eduardo Alexandre Barros e Silva, Davis, CA (US);
Toshihisa Kawai, Brookline, MA (US);
David J. Mooney, Sudbury, MA (US);
Assignees:
President and Fellows of Harvard College, Cambridge, MA (US);
Forsyth Dental Infirmary for Children, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/39 (2006.01); A61K 39/102 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0008 (2013.01); A61K 39/0011 (2013.01); A61K 39/102 (2013.01); A61K 39/35 (2013.01); A61K 39/39 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/577 (2013.01); A61K 2039/70 (2013.01);
Abstract
Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby leading suppression of inflammation. The compositions and methods are useful to reduce the severity of autoimmunity, chronic inflammation, allergy, and periodontal disease.