The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Mar. 06, 2015
Applicants:
Cleveland Clinic Foundation, Cleveland, OH (US);
Cleveland Biolabs, Inc., Buffalo, NY (US);
Inventors:
Alexander Shakhov, Orchard Park, NY (US);
Andrei Gudkov, East Aurora, NY (US);
Elena Feinstein, Buffalo, NY (US);
Assignees:
CLEVELAND CLINIC FOUNDATION, Cleveland, OH (US);
CLEVELAND BIOLABS, INC., Buffalo, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 47/48 (2006.01); A61K 38/16 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 38/164 (2013.01); A61K 45/06 (2013.01); A61K 47/481 (2013.01); A61K 47/48038 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/00 (2013.01);
Abstract
The use of lipopeptides comprising variable groups defined as H or optionally substituted C-Caliphatic and a peptide of one of the following amino acid sequences: GEESN (SEQ ID NO: 17), QGEESNDK (SEQ ID NO: 20), and VQGEESNDK (SEQ ID NO: 21). The use of the lipopeptides for activating Toll-like receptors (TLRs) in cells is described.