The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2016
Filed:
Feb. 22, 2013
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 8/28 (2006.01); A61K 38/26 (2006.01); A61P 5/50 (2006.01); A61P 3/08 (2006.01); A61P 3/10 (2006.01); A61P 7/12 (2006.01); C07K 14/605 (2006.01); A61K 31/18 (2006.01); A61K 31/404 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
A61K 31/18 (2013.01); A61K 31/404 (2013.01); A61K 31/4985 (2013.01); A61K 38/26 (2013.01);
Abstract
Provided herein are methods for increasing insulin secretion from beta cells. Also provide herein are methods comprising administering to a subject in need of increased insulin secretion a composition comprising a compound that directly or indirectly activates adenylate cyclase and an E prostanoid 3 (EP3) receptor antagonist that attenuates G alpha-i-subfamily (GSIS)-mediated adenylate cyclase inhibition.