The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Jun. 13, 2013
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventor:
E. James Petersson, Wynnewood, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, OR (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/113 (2006.01); C12P 21/00 (2006.01); A61K 38/00 (2006.01); C07K 1/02 (2006.01); C07K 1/13 (2006.01); C07C 247/16 (2006.01); C07C 255/03 (2006.01); C07D 311/08 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); A61K 38/00 (2013.01); C07C 247/16 (2013.01); C07C 255/03 (2013.01); C07D 311/08 (2013.01); C07D 473/34 (2013.01); C07K 1/026 (2013.01); C07K 1/113 (2013.01); C07K 1/13 (2013.01);
Abstract
The invention includes a selective method of modifying the N-terminus of a protein using an aminoacyl tRNA transferase. In certain embodiments, the method comprises contacting a solution of the protein or peptide with a transferase and a derivative of a molecule, whereby the N-terminus of the protein or peptide is derivatized with the molecule.