The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
May. 16, 2012
Ezio Bonvini, Rockville, MD (US);
Bhaswati Barat, Derwood, MD (US);
Ling Huang, Bethesda, MD (US);
Leslie S. Johnson, Darnestown, MD (US);
Ezio Bonvini, Rockville, MD (US);
Bhaswati Barat, Derwood, MD (US);
Ling Huang, Bethesda, MD (US);
Leslie S. Johnson, Darnestown, MD (US);
MacroGenics, Inc., Rockville, MD (US);
Abstract
The present invention is directed to a polypeptide (for example, an antigen-binding molecule) that comprises a polypeptide portion of a deimmunized serum-binding protein capable of binding to said serum protein. The presence of the serum-binding protein extends the serum half-life of the polypeptide, relative to the serum half-life of the polypeptide if lacking the polypeptide portion of the deimmunized serum-binding protein. The invention also pertains to methods and uses that employ such molecules.