The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Jan. 10, 2013
Applicants:
Nan Lin, St. Louis, MO (US);
Natalie Sealover, St. Louis, MO (US);
Henry George, St. Louis, MO (US);
Kevin Kayser, St. Louis, MO (US);
Inventors:
Nan Lin, St. Louis, MO (US);
Natalie Sealover, St. Louis, MO (US);
Henry George, St. Louis, MO (US);
Kevin Kayser, St. Louis, MO (US);
Assignee:
SIGMA-ALDRICH CO. LLC, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 16/00 (2006.01); C12P 21/00 (2006.01); C12N 9/10 (2006.01); C12P 21/04 (2006.01); C12N 15/63 (2006.01); C12N 15/67 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C12N 9/1051 (2013.01); C12P 21/005 (2013.01); C12P 21/02 (2013.01); C12Y 204/01101 (2013.01); C07K 2317/14 (2013.01); C07K 2317/41 (2013.01); Y02P 20/52 (2015.11);
Abstract
The present invention provides cell lines deficient in mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase I (Mgat1). Also provided are methods for producing the Mga1 deficient cell lines and methods for using the Mgat1 deficient cell lines for the production of recombinant proteins having simple glycoforms.