The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Dec. 21, 2012
Applicant:
New York University, New York, NY (US);
Inventors:
Paramjit S. Arora, Huntington, NY (US);
Anupam Patgiri, New York, NY (US);
Stephen Joy, New York, NY (US);
Assignee:
New York University, New York, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/56 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 7/50 (2006.01); C07K 7/54 (2006.01); A61K 38/02 (2006.01); A61K 38/31 (2006.01);
U.S. Cl.
CPC ...
C07K 7/56 (2013.01); A61K 38/02 (2013.01); C07K 2/00 (2013.01); C07K 4/00 (2013.01); C07K 7/50 (2013.01); C07K 7/54 (2013.01); A61K 38/31 (2013.01);
Abstract
The present invention relates to peptidomimetics having a stable, internally constrained protein secondary structure, where the peptidomimetics contain a hydrogen bond surrogate in the internal constraint, and at least one beta amino acid. Methods for promoting cell death using peptidomimetics that inhibit p53/hDM2 are also disclosed.